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Patent Use Can Foramen Ovale Cause Stroke In Kings
State:
Multi-State
County:
Kings
Control #:
US-003HB
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Patent foramen ovale is prevalent in 20–34% of the population1 and are generally benign and asymptomatic. Occasionally, they can give rise to systemic emboli, which can cause both ocular and cerebral ischaemic events, such as cryptogenic strokes.
Evidence suggests PFO has a genetic predisposition. Genetic variants associated with PFO would serve as biomarkers used for screening high risk individuals. Specific genes that contribute to FO closure are largely unknown. This is attributed to our incomplete understanding of the physiological process of FO closure.
Rarely, a patent foramen ovale can cause a significant amount of blood to go around the lungs. This lowers blood oxygen levels, a condition called hypoxemia. Stroke. Sometimes small blood clots in veins may travel to the heart.
While PFO usually doesn't cause any noticeable symptoms, it can be serious. PFO increases the risk of a stroke caused by deep-vein thrombosis (DVT), a blood clot that can form in the veins of the legs.
Stroke is the major possible complication of a PFO. People who have a PFO are slightly more likely to have a stroke than people who don't. A PFO is more likely to be involved in a stroke of a younger adult. That's because younger people don't have as many risk factors for stroke from other causes.
The RoPE score ranges from 0 to 10, with scores of 0 to 3 indicating a negligible likelihood that the stroke is attributable to the PFO and a score of 10 indicating an approximately 90% probability that the stroke is attributable to the PFO.
These findings indicate that 60,000 to 80,000 cryptogenic ischemic strokes per year in the US occur in patients with a PFO.
Possible Complications Some people may have a condition shortness of breath and low arterial blood oxygen levels when sitting or standing. This is called platypnea-orthodeoxia. This is rare. Rarely, people with PFOs may have a higher rate of a certain type of stroke (called paradoxical thromboembolic stroke).