Conditions Alzheimer's disease and other memory disorders. Ataxia. Huntington's disease. Parkinson's disease. Motor neuron disease. Multiple system atrophy. Progressive supranuclear palsy.
A major new study released by The Lancet Neurology shows that, in 2021, more than 3 billion people worldwide were living with a neurological condition. The World Health Organization (WHO) contributed to the analysis of the Global Burden of Disease, Injuries, and Risk Factor Study (GBD) 2021 data.
Currently available therapies for neurodegenerative diseases. While there is no definitive cure for most neurodegenerative diseases, there are various therapies and interventions available to help manage symptoms, slow disease progression, and improve the quality of life for individuals affected by these conditions.
Neurological disorders are the leading cause of physical and cognitive disability across the globe, currently affecting approximately 15% of the worldwide population 1. Absolute patient numbers have considerably climbed over the past 30 years.
If significant neuronal loss is lacking, some other pathological features of neurodegeneration, such as the presence of Lewy bodies, so typical of PD, and neurofibrillary tangles (NFTs) and senile plaques, so typical of AD, can be detected in brains of asymptomatic aged individuals (36, 37).
Examples include amyloid-beta (Aβ), phosphorylated tau (pTau), alpha-synuclein (α-syn), neurofilament light chain (NfL, and glial fibrillary acidic protein (GFAP), often used in combination. Another potential use is in subjective cognitive decline (Zetterberg and Schott, 2022).