PFOs may be found in association with: Atrial septal aneurysms (a redundancy of the interatrial septum) Eustachian valves (a remnant of the sinus venosus valve) Chiari networks (filamentous strands in the right atrium)
Small holes between the upper chambers of the heart may be categorized as an atrial septal defect (ASD) or patent foramen ovale (PFO). An ASD is a congenital heart defect, a condition that you are born with. PFOs can occur only after birth when the foramen ovale fails to close.
Patent foramen ovale is prevalent in 20–34% of the population1 and are generally benign and asymptomatic. Occasionally, they can give rise to systemic emboli, which can cause both ocular and cerebral ischaemic events, such as cryptogenic strokes.
PFO is a subclass of the ostium secundum defect and is not considered a defect of the "true septum." PFO is the most common septal anomaly, occurring when the septum primum and septum secundum fail to approximate and close the foramen ovale after the child takes its first breath.
However, a PFO can allow those clots to bypass the lungs and cross to the left side of the heart. From there, they can be pumped to the brain, causing a stroke. People who have a PFO and have had an embolic stroke of unknown cause may be at an increased risk for having a second stroke.
Possible complications of patent foramen ovale may include: Low blood oxygen. Rarely, a patent foramen ovale can cause a significant amount of blood to go around the lungs. This lowers blood oxygen levels, a condition called hypoxemia. Stroke. Sometimes small blood clots in veins may travel to the heart.
The foramen ovale plays a vital role in sustaining life in-utero; however, a patent foramen ovale (PFO) after birth has been associated with pathologic sequelae in the systemic circulation including stroke/transient ischemic attack (TIA), migraine, high altitude pulmonary edema, decompression illness, platypnea– ...
When should a PFO be closed? A healthcare provider may recommend a PFO closure procedure if: You've had a transient ischemic attack (TIA) more than once. You've had cryptogenic (from an unknown cause) strokes more than once.
A healthcare provider may recommend a PFO closure procedure if: You've had a transient ischemic attack (TIA) more than once. You've had cryptogenic (from an unknown cause) strokes more than once. You have a low level of oxygen in your blood.