Rarely, a patent foramen ovale can cause a significant amount of blood to go around the lungs. This lowers blood oxygen levels, a condition called hypoxemia. Stroke. Sometimes small blood clots in veins may travel to the heart.
Most PFOs don't need to be closed. Most PFOs cause no symptoms or complications. Larger PFOs may cause stroke. People with symptomatic or large PFOs may benefit from a procedure to close the hole.
While PFO usually doesn't cause any noticeable symptoms, it can be serious. PFO increases the risk of a stroke caused by deep-vein thrombosis (DVT), a blood clot that can form in the veins of the legs.
Patent foramen ovale lets a small amount of blood flow between the flaps connecting your right and left atrium. Normally these flaps stop blood from flowing between them. Usually, patent foramen ovale causes no problems. But PFO may let a blood clot travel from the right to the left side of your heart.
Stroke is the major possible complication of a PFO. People who have a PFO are slightly more likely to have a stroke than people who don't. A PFO is more likely to be involved in a stroke of a younger adult. That's because younger people don't have as many risk factors for stroke from other causes.
The finding of a thrombus in transit () through a patent foramen ovale (PFO) is extremely rare, and its treatment may include anticoagulation, fibrinolysis, or cardiac surgery.