If a PFO exists, a little blood can flow between the atria through the flaps. This flow is not normal. The condition is most important because it raises the risk for stroke. Blood clots can travel from the right atrium to the left atrium and out to blood vessels of the body.
The cause of a PFO is unknown. There are no known risk factors. It can be found along with other heart abnormalities such as atrial septal aneurysms or Chiari network.
Abstract. Patent foramen ovale (PFO) is implicated in platypnea-orthodeoxia, stroke and decompression sickness (DCS) in divers and astronauts. However, PFO size in relation to clinical illness is largely unknown since few studies evaluate PFO, either functionally or anatomically.
Rarely, a patent foramen ovale can cause a significant amount of blood to go around the lungs. This lowers blood oxygen levels, a condition called hypoxemia. Stroke. Sometimes small blood clots in veins may travel to the heart.