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  • Review Of Toxicological Information- Cervarix (pdf - 199kb) - Fda

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REVIEW MEMORANDUMTOXICOLOGY OF MPL To: Robin Levis, Ph.D., DVP, OVRR, CBER, FDA From: Elizabeth M. Sutkowski, Ph.D., DVRPA, OVRR, CBER, FDA Through: Martin Green, Ph.D., DVRPA, OVRR, CBER, FDA Subject:.

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GlaxoSmithKline (GSK) announced today that the U.S. Food and Drug Administration (FDA) has approved Cervarix® [Human papillomavirus bivalent (types 16 and 18) vaccine, recombinant] for the prevention of cervical pre-cancers and cervical cancer associated with oncogenic human papillomavirus (HPV) types 16 and 18 for use ...

Note that the VIS no longer specifies “-9.” This is because -9 will soon be the only HPV vaccine available in the U.S., as Cervarix and (quadrivalent HPV vaccine) will no longer be sold in the United States.

On October 16, 2009, the Food and Drug Administration (FDA) licensed bivalent human papillomavirus vaccine (HPV2; Cervarix, GlaxoSmithKline) for use in females aged 10 through 25 years. Cervarix is the second human papillomavirus (HPV) vaccine licensed for use in females in the United States.

Immunization with CERVARIX consists of 3 doses of 0.5-mL each, by intramuscular injection 29 ing to the following schedule: 0, 1, and 6 months. The preferred site of administration is 30 the deltoid region of the upper arm.

Based on the review of the available information, at the time of the withdrawal, the Agency had concerns and its provisional opinion was that Cervarix could not have been authorised for the prevention of head and neck cancers. In particular, the Agency had concerns about the design of the main study.

In particular, the Agency had concerns about the design of the main study. The Agency noted that the way prevention of persistent HPV infection in the mouth and throat was measured was not adequate as testing was only done once and not repeated over time.

"GSK recently made the decision to stop supplying Cervarix in the US due to very low market demand," a company spokesperson told the newsletter Fierce Pharma.

On October 16, 2009, the Food and Drug Administration (FDA) licensed bivalent human papillomavirus vaccine (HPV2; Cervarix, GlaxoSmithKline) for use in females aged 10 through 25 years. Cervarix is the second human papillomavirus (HPV) vaccine licensed for use in females in the United States.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232