Get The Impact Of Hypodontia On The Oral Health-related Quality Of Life In ... - Etheses Bham Ac

Causes and Risk Factors Dental defects are the result of increased maternal age, low birth weight, multiple births, early exposure to certain infections, and trauma or medication. Hypodontia is usually the result of hereditary disorders such as ectodermal dysplasia and Down's syndrome.

Hypodontia tends to be an inherited issue but can be affected by environmental factors as well. These factors are having low birth weight, incidences of rubella, maternal smoking, and advanced maternal age.

EDA, EDAR and EDARADD genes are indeed responsible both for isolated or syndromic hypo/oligodontia. Many other genes are involved in hypo/oligodontia such as MSX1, PAX9, IRF6, GREM2, AXIN2, LRP6, SMOC2, LTBP3, PITX2, and WNT10B.

Hypodontia associated syndromes Cleft lip or cleft palate. Low birth weight. Genetic disorders, such as Down syndrome or ectodermal dysplasia. Infectious diseases, such as candida or rubella. Chemotherapy. Radiation therapy.

Besides an unfavorable appearance, patients with missing teeth may suffer from malocclusion, periodontal damage, insufficient alveolar bone growth, reduced chewing ability, inarticulate pronunciation and other problems.

As your mouth is the entry point to your respiratory and digestive tracts, it is not long before harmful bacteria begin to spread systemically. Strong research suggests that poor oral health and oral infections may lead to heart and lung diseases, diabetes, stroke, and premature births.

Oral health is closely related with general health and people's quality of life (QoL), through affecting their oral functions and social interactions. For example, dental caries may cause impaired chewing, decreased appetite, sleep problems, and poor school and work performance.