Get Lethal White Overo - Red Factor - Agouti

Overo lethal white syndrome is a genetic condition that affects certain horse breeds, particularly those with the Lethal White Overo color pattern. Horses with this syndrome are born with a completely white coat but typically suffer from severe gastrointestinal issues. Unfortunately, this condition is often fatal shortly after birth. Understanding the implications of the Lethal White Overo - Red Factor - Agouti gene is crucial for breeders to ensure the health of their horses.

While most horses diagnosed with lethal white syndrome do not survive, there have been rare cases of horses that have lived past the typical lifespan. These cases often involve intensive care and management. However, it is essential to note that the prognosis is generally poor. If you are dealing with this issue, US Legal Forms can help you understand your options and provide necessary resources.

Lethal white syndrome primarily affects certain breeds known for their association with the Lethal White Overo color pattern. Breeds such as the American Paint Horse, Quarter Horse, and Thoroughbred are particularly susceptible. Awareness of this syndrome is crucial for breeders, as it can have serious implications for foal health. For comprehensive information on this topic, consider visiting US Legal Forms.

Yes, a red horse can carry the agouti gene. This gene affects the distribution of black pigment in the horse's coat. Therefore, even if a horse appears red, it might still possess the agouti gene, which can influence its offspring's color. Understanding these genetic combinations is essential for breeders interested in Lethal White Overo - Red Factor - Agouti.

A mutation in the middle of the EDNRB gene, Ile118Lys, causes lethal white syndrome. In this mutation, a "typo" in the DNA mistakes isoleucine for lysine. The resulting EDNRB protein is unable to fulfill its role in the development of the embryo, limiting the migration of the melanocyte and enteric neuron precursors.

There isn't a treatment for OLWS. Surgery to bypass the intestinal damage remains unsuccessful. Euthanasia is advised for all OLWS foals with colic.

2) Overo (O-vair'-o) appears to be a colored horse with jagged white markings usually originating on the animal's side or belly, spreading toward the neck, tail, legs, and back. The color appears to frame the white spots. Thus, an Overo often has a dark tail, mane, legs, and backline.

Over 94 percent of framed overos are carriers. Framed overos have white patches centered on the body and neck. Horses from overo lineage but they themselves don't have white markings, can still carry the gene. Up to 20 percent of broodstock without excessive white carry the gene.

What are the clinical signs of overo lethal white foal syndrome? Affected foals exhibit an all-white coat color with pink skin and blue eyes. They may also be deaf. Although some foals may appear normal at birth, they have trouble passing manure.