Get SCNIR Yearly Summary Patient Information 2000-2024

Benign ethnic neutropenia (BEN), also known as benign familial neutropenia, benign neutropenia of the black, and chronic benign idiopathic neutropenia, is an asymptomatic condition commonly observed in individuals of African, Arab, as well as Ethiopian and Yemenite Jewish descent.

The prognosis is good, with a benign course; however, 10% of patients will experience life-threatening infections. The treatment for cyclic neutropenia is daily G-CSF.

Primary autoimmune neutropenia usually resolves on its own. In approximately 95% of children with AIN, neutrophil counts return to normal by ages two or three. Almost all cases of primary AIN resolve by age 11.

Severe neutropenia or agranulocytosis, defined as an absolute neutrophil count of less than 0.5 × 109/L (<500/μL), is uncommon but can cause morbidity and mortality from infections.

Severe chronic neutropenia (SCN) is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the bloodstream (neutropenia) not explained by medication use, infections or another underlying health condition like blood cancers or systemic autoimmune diseases associated ...

Moderate to severe neutropenia may increase your risk of infection. Without treatment, severe neutropenia can be life-threatening.

Diagnosis. The diagnosis of autoimmune neutropenia is based on blood tests demonstrating neutropenia and the presence of granulocyte-specific antibodies. In some cases, tests for granulocyte-specific antibodies must be repeated several times before a positive result is seen.