Get CA1 NI 2011-2024

Within the hippocampal memory system, CA1 neurons are critically involved the formation, consolidation, and retrieval of hippocampal-dependant memories. Recent high-resolution volumetry did show an association between CA1 volume and episodic memory retrieval (38).

CA1 neurons are suggested to express Ih at higher levels than CA3 pyramidal cells ensuring larger responses to hyperpolarization and thus more prominent resonance peaks. With a strong Ih, excitatory inputs during theta can delay firing, an effect counteracted by phasic inhibitory currents during theta oscillations.

CA1 neurons are suggested to express Ih at higher levels than CA3 pyramidal cells ensuring larger responses to hyperpolarization and thus more prominent resonance peaks. With a strong Ih, excitatory inputs during theta can delay firing, an effect counteracted by phasic inhibitory currents during theta oscillations.

CA1 is closer to the output region of the hippocampus and it is important for representing space in the environment, so that individual cells in the CA1 region encode for space and therefore long-term memory for space and attentional modulation of space importantly involves the CA1 region.

The CA1, CA2, and CA3 regions are the principal pyramidal cell fields in the hippocampus (Figure 3) and are often the focus of research concerned with memory encoding and retrieval (McNaughton and Morris, 1987; Chevaleyre and Siegelbaum, 2010).

Abstract. The pyramidal neurons of the hippocampal CA1 region are essential for cognitive functions such as spatial learning and memory, and are selectively destroyed after cerebral ischemia.

CA1. CA1 is the first region in the hippocampal circuit, from which a major output pathway goes to layer V of the entorhinal cortex. Another significant output is to the subiculum.

Abstract. The pyramidal neurons of the hippocampal CA1 region are essential for cognitive functions such as spatial learning and memory, and are selectively destroyed after cerebral ischemia.