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Treatment typically consists of applications of bee stings three times a week, about every other day. Treatments are applied over the body on a rotating basis so that a former treatment area is not treated again until all symptoms of the previous stings have healed.

Therapy with bee venom involves receiving up to 40 stings in a session. Ice is used to numb the skin and to reduce pain. There may be more than one session per week. The theory behind the treatment is that bee stings cause inflammation.

Evidence from animal studies suggests that bee-venom therapy might help reduce symptoms of autoimmune conditions, such as lupus, encephalomyelitis, and rheumatoid arthritis, by decreasing inflammation and bolstering your immune response ( 19 , 20 ).

For reducing the severity of allergic reactions to bee stings: Healthcare providers give bee venom as a shot (by injection) to "desensitize" people who are allergic to bee stings. Purified bee venom for under-the-skin injection is an FDA approved product.

Bee venom has been used to treat many diseases because of its anti-inflammatory and analgesic effects. However, the secretions of bee venom can also cause life-threatening adverse reactions.

Evidence from animal studies suggests that bee-venom therapy might help reduce symptoms of autoimmune conditions, such as lupus, encephalomyelitis, and rheumatoid arthritis, by decreasing inflammation and bolstering your immune response ( 19 , 20 ).

Bee venom (BV) is essentially a complex mixture, composed of peptides, toxic proteins, and other bioactive components. The main component is a 26-amino acid, hemolytic peptide called melittin, which constitutes about 50–60% of the venom by dry weight and is responsible for most of the observed effects of BV.

Bee venom contains several active molecules such as peptides and enzymes that have advantageous potential in treating inflammation and central nervous system diseases, such as Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis.