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Why was banned?
First, because safety cannot be assured. Bayer withdrew cerivastatin in August, 2001, after the occurrence of unexpected cases of fatal rhabdomyolysis. The 80 mg dose of was withdrawn by AstraZeneca because of safety concerns. Some critics are even anxious about the 40 mg dose.
What is the difference between and ?
One significant difference between and is their metabolism pathway. is metabolized extensively in the liver by CYP3A4 – an enzyme that resides in the liver and gastrointestinal tract.
What is the drug used for?
is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of cholesterol that may build up on the walls of the arteries and block blood flow to the heart, brain, and other parts of the body.
Is there a problem with ?
® () may cause serious side effects, including: Muscle pain, tenderness, and weakness (myopathy). Muscle problems, including muscle breakdown, can be serious in some people and rarely cause kidney damage that can lead to death.
Is discontinued?
Mylan discontinued all presentations. Sun Pharma discontinued all presentations.
Why was taken off the market?
interacted dangerously with the blood-thinner , commonly used by heart-disease patients; one - interaction resulted in a hemorrhage. Some studies show that only one-tenth of the actual cases are reported to the FDA. The fact that so few patients on the 20 or 40 mg.
What is 20 mg used for?
is used to correct the levels of fatty substances in the blood called lipids, the most common of which is cholesterol. There are different types of cholesterol found in the blood – 'bad' cholesterol (LDL-C) and 'good' cholesterol (HDL-C).
What is an alternative to ?
FDA-approved statins include: () ( XL) () () . () ()
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