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Get Antisense Oligonucleotide Modulation Of Raf Gene Expression - European Patent Office - Ep 0863911 B1
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How to fill out the ANTISENSE OLIGONUCLEOTIDE MODULATION OF Raf GENE EXPRESSION - European Patent Office - EP 0863911 B1 online
This guide provides clear and comprehensive instructions for filling out the ANTISENSE OLIGONUCLEOTIDE MODULATION OF Raf GENE EXPRESSION form as specified by the European Patent Office. By following these steps, users can ensure that their filings are complete and accurate.
Follow the steps to effectively complete the form online.
- Press the ‘Get Form’ button to obtain the necessary form and open it in your preferred document editor.
- Review the header section of the form to ensure it includes the correct title: 'ANTISENSE OLIGONUCLEOTIDE MODULATION OF Raf GENE EXPRESSION - European Patent Office - EP 0863911 B1'.
- Fill out the international application number field with 'PCT/US96/08165' and confirm your application number as '96916859.0'.
- Enter the filing date as '31.05.1996' in the appropriate section.
- Provide details of the proprietors, including ISIS PHARMACEUTICALS, INC. and Novartis AG, ensuring all necessary identification information is present.
- Outline the designated contracting states relevant to your application, such as AT, BE, CH, DE, and others listed.
- In the claims section, specify oligonucleotides that modulate Raf gene expression, clearly indicating any modifications.
- Check that all inventor names are correctly listed — Brett P. Monia, Pierre Martin, and Karl-Heinz Altmann.
- Finally, review the entire form for completeness, ensuring all fields are filled accurately without omissions.
- Once satisfied with the accuracy and completeness, save your changes, and utilize options to download, print, or share the form as necessary.
Complete your submission by filing the form online today.
RNA interference and antisense oligonucleotides downregulate gene expression by enzyme-dependent degradation of targeted mRNA. Steric blocking oligonucleotides block access of cellular machinery to pre-mRNA and mRNA without degrading the RNA.
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