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  • Research Paper Of Evaluation And Formulation Of Fast Dissolving Tablet

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R.B.*, Baria A.H.1, Tank H.M.2, Faldu S.D.1 *1 S. J. Thakkar Pharmacy College, Nr. N.R.I. Bungalows, Rajkot. 2 S. S. Institute of Pharmaceutical Education and Research, Hadala, Rajkot. * Email: rbparmar82 yahoo.co.in Abstract: , an antiemetic drug, has been used as an add-on treatment in adults and children. As precision of dosing and patient s compliance become important prerequisite for quick relief from emesis, there is a need to develop a formulation for this drug which o.

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Novel technologies with improved performance, patient compliance, and enhanced quality have emerged in the recent past. The fast dissolving drug delivery system started gaining popularity and acceptance as a new drug delivery system because they are easy to administer and lead to better patient compliance.

Mouth fast dissolving tablets of Cetirizine Hydrochloride were prepared by direct compression method using sodium starch glycolate, croscarmellose and crospovidone as superdisintegrants in different concentrations and Pearlitol as directly compressible diluent.

High dosage, highly water soluble, poorly compressible and hygroscopic drugs represent the greatest difficulty in a dispersible compressible formulation. The excipients must be carefully selected to produce an array of tablets with high compressibility and low aqueous solubility and hygroscopicity.

The fast disintegration of ODTs is just as much an advantage as it is a disadvantage. Since the medication is absorbed so quickly in the oral cavity, ODTs cannot support controlled or extended-release medication.

The major disadvantages of FDTs is related to the mechanical strength of tablets. FDT are very porous and soft molded metrics or compressed in a tablet with low compression, which makes tablet friable and brittle which difficult to handle.

Fast disintegrating tablets (FDTs) are meant for administration to the patients who cannot swallow, such as the elderly, stroke victims, bedridden patients, patients affected by renal failure, and patients who refuse to swallow, such as pediatric, geriatric, and psychiatric patients.

Criteria for Fast dissolving Drug Delivery System: The tablets should ➢ Not require water to swallow, but it should dissolve or disintegrate in the mouth in matter of seconds. ➢ Be compatible with taste masking. ➢ Be portable without fragility concern. ➢ Have a pleasant mouth feel.

Nevertheless, ODT's have some disadvantages like limited tablet weight, short disintegration time, high cost, and packaging problems. Orally disintegrating tablets may be evaluated as a first option for pediatric and geriatric patients who have swallowing problem.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232