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Microsphere Brachytherapy Sources and Devices Licensing Guidance - TheraSphere and SIRSpheres Yttrium-90 Y-90 microspheres are manual brachytherapy sources used for permanent brachytherapy implantation therapy.

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During brachytherapy the principles of conformal radiotherapy should be implemented, the aim of which is to sum the maximum possible dose of radiation to the tumor and decrease the dose load in adjacent organs and tissues, which allows reducing the frequency of radiation damage at treatment of primary tumors.

SIR-Sphere consists of resin microspheres coated with Y-90 while TheraSphere contains insoluble glass microspheres with Y-90 as an intricate part of the glass matrix.

Yttrium-90 (Y-90) microspheres are manual brachytherapy sources used for permanent implantation therapy. Y-90 microspheres are regulated under 10 CFR 35.1000 “Other Medical Uses of Byproduct Material or Radiation from Byproduct Material.”

Nordion Inc. (TSX: NDN) (NYSE: NDZ) is a global health science company that provides market-leading products used for the prevention, diagnosis and treatment of disease.

Some radioactive sources used for brachytherapy are iridium-192 (half-life = 74.17 days), iodine-125 (half-life = 60.25 days), and palladium-103 (half-life = 16.96 days). These radionuclides have relatively short half-lives, permitting brachytherapy seeds to be inserted into a cancerous tumor and never removed.

Yttrium-90 is produced by the nuclear decay of strontium-90 which has a half-life of nearly 29 years and is a fission product of uranium used in nuclear reactors. As the strontium-90 decays, chemical high-purity separation is used to isolate the yttrium-90 before precipitation.

This is an outline of radioactive sources that are currently used in brachytherapy, such as Cs- 137, Ir-192, Sr-90, Ra-226, Rn-222, Co-60, I-131, I-125, Pd-103, Tu-106 and Cf-252.

The Yttrium-90 irradiates from within and can be viewed as "internal" radiation or "brachytherapy." Radioembolization is a palliative, not a curative, treatment. Patients may benefit by extending their lives and improving their quality of life.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232