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S40532 Osteoarthritis is a common chronic and degenerative osteoarthropathy,1–3 characterized by primary or secondary degeneration of the articular cartilage with hyperplasia of the bone under the cartilage.4–6 The main clinical manifestations are chronic arthralgia, anchylosis, and arthroncus with functional disorder. The disease generally involves the knees, spine, and interphalangeal joints. Arthritis affects nearly 50 million people in the USA,7 with prevalence rising as the populatio.

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