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  • Effects Of The Isoform-specific Characteristics Of Atf6 And Atf6 ... - Jbc

Get Effects Of The Isoform-specific Characteristics Of Atf6 And Atf6 ... - Jbc

Ter J. Belmont and Christopher C. Glembotski J. Biol. Chem. published online May 23, 2007 Find articles, minireviews, Reflections and Classics on similar topics on the JBC Affinity Sites. Alerts: When this article is cited When a correction for this article is posted Click here to choose from all of JBC's e-mail alerts This article cites 0 references, 0 of which can be accessed free at http://www.jbc.org/content/early/2007/05/23/jbc.M701213200.citation.full.html#ref-list-1 Downloaded f.

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Filling out the form regarding the effects of the isoform-specific characteristics of ATF6 α and ATF6 β is crucial for comprehensively understanding the ER stress response and gene expression. This guide provides clear and user-friendly instructions to assist you through the process seamlessly.

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ATF6 is an ER-membrane-bound transcription factor activated by ER stress-induced proteolysis which consists of two closely related factors, ATF6alpha and ATF6beta, in mammals. ATF6alpha but not ATF6beta plays an important role in transcriptional control.

ATF6 is activated in response to ER stress through a mechanism involving reduction and monomerization of ATF6 oligomers, increased trafficking to the Golgi, and subsequent proteolytic processing by Site 1 and Site 2 proteases (S1P and S2P, respectively) [24].

The UPR consists of three effector proteins: PKR like ER kinase (PERK), Inositol-requiring enzyme 1 (IRE1), and Activating Transcription Factor 6 (ATF6), which aim to resolve ER stress by transiently inhibiting global translation, expanding the ER capacity and upregulating important ER-resident chaperones, such as ...

ATF6 is a type 2 membrane protein with a single transmembrane domain (Figure 1). Its NH2-terminal cytosolic domain is a transcription factor of the bZIP family.

The general transcription factors comprise at least six distinct species: TFII A, B, D, E, F, and H (see Fig. 7.1b). TFIID (300–750 kDa) is a multiprotein complex composed of a TATA (box)-binding protein (TBP) and up to 13 TBP-associated factors (TAFs).

Activating transcription factor 4 (ATF4) belongs to the ATF/CREB (activating transcription factor/cyclic AMP response element binding protein) family of basic region-leucine zipper (bZip) transcription factors, which have the consensus binding site cAMP responsive element (CRE).

Atf-6 Regulates Lifespan through ER-Mitochondrial Calcium Homeostasis. Multiexon deletion alleles of ATF6 linked to achromatopsia. The Epstein-Barr Virus Lytic Protein BMLF1 Induces Upregulation of GRP78 Expression through ATF6 Activation.

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Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
Privacy Notice
Legal Hub
Content Takedown Policy
Bug Bounty Program
About Us
Blog
Affiliates
Contact Us
Delete My Account
Site Map
Industries
Forms in Spanish
Localized Forms
State-specific Forms
Forms Kit
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate WorkFlow
DocHub
Instapage
Social Media
Call us now toll free:
+1 833 426 79 33
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232