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  • Journal Of Antimicrobial Chemotherapy Advance Access Published September 10, 2009 - Jac

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S of a sequence-selective, DNA minor groove cross-linking pyrrolobenzodiazepine dimer Marie Doyle1, Eva-Anne Feuerbaum1, Keith R. Fox2, Jason Hinds3, David E. Thurston1 and Peter W. Taylor1* 1 Received 29 April 2009; returned 22 June 2009; revised 6 August 2009; accepted 10 August 2009 Objectives: ELB-21 is a pyrrolo 2,1-c 1,4 benzodiazepine dimer with potent antistaphylococcal activity; it binds covalently to guanine residues on opposing strands of duplex DNA, interfering with regulatory prot.

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There are six major modes of action: (1) interference with cell wall synthesis, (2) inhibition of protein synthesis, (3) interference with nucleic acid synthesis, (4) inhibition of a metabolic pathway, (5) inhibition of membrane function, (6) inhibition of ATP Synthase (Fig.

Various antimicrobial agents act by interfering with (1) cell wall synthesis, (2) plasma membrane integrity, (3) nucleic acid synthesis, (4) ribosomal function, and (5) folate synthesis.

The mechanisms of resistance can be broken down into the following: Enzyme inactivation and modification. Modification of the antibiotics target site. Overproduction of the target. Replacement of the target site. Efflux and reduced permeability.

Journal of Antimicrobial Chemotherapy Publication detailsImpact factor5.2 (2022)Standard abbreviations ISO 4 (alt) · Bluebook (alt1 · alt2) NLM (alt) · MathSciNet (alt )ISO 4J. Antimicrob. Chemother.Indexing CODEN (alt · alt2) · JSTOR (alt) · LCCN (alt) MIAR · NLM (alt) · Scopus13 more rows

Inhibition of Cell Wall Synthesis (most common mechanism) Inhibition of Protein Synthesis (Translation) (second largest class) Alteration of Cell Membranes. Inhibition of Nucleic Acid Synthesis.

The 2023-2024 Journal's Impact IF of Journal of Antimicrobial Chemotherapy is 5.758, which is just updated in 2024.

Inhibitors of the biosynthesis of the bacterial cell wall 2. Inhibitors of the bacterial protein synthesis 3. Inhibitors of the nucleic acid metabolism 4. Membrane-active antibiotics.

Antimicrobial chemotherapy is a broad term that includes all medications used to target bacteria, viruses, parasites, funguses, and other microorganisms that can cause infections in your body. Antimicrobial chemotherapy can include everything from injected antiviral medications to at-home oral antibiotics.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
Content Takedown Policy
Bug Bounty Program
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
Industries
Forms in Spanish
Localized Forms
State-specific Forms
Forms Kit
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
+1 833 426 79 33
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232