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Y, Daymand Medical College and Hospital, Ludhiana 141 001 Abstract Background. Continuous peritoneal lavage, staged laparotomies and radical peritoneal debridement have been used to reduce mortality from severe abdominal sepsis. Recently, open abdomen technique using a 'zipper' with or without mesh for abdominal lavage has shown promising results. Aims: To evaluate open abdominal technique using a zipper in patients with advanced diffuse peritonitis with impending o r established multiple organ.

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