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T DNA Experiments (including Transgenic Animals) Frequently Asked Questions and Definitions The Guidelines for Research Involving rDNA Molecules (NIH Guidelines) are published in the Federal Register and specify practices for constructing and handling DNA molecules and organisms and viruses containing rDNA molecules. The Institutional Biosafety Committee (IBC) is responsible for approving risk assessment and the biosafety containment level for such experiments. The NIH Guidelines also identify r.

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