Get Protocol For A Randomised Controlled Trial Investigating The - Trials

The randomised control trial (RCT) is a trial in which subjects are randomly assigned to one of two groups: one (the experimental group) receiving the intervention that is being tested, and the other (the comparison group or control) receiving an alternative (conventional) treatment (fig 1).

The RCT is the most scientifically rigorous method of hypothesis testing available,5 and is regarded as the gold standard trial for evaluating the effectiveness of interventions.

Of all the many ways research can be conducted, the gold standard level of proof where treatments and therapies are concerned is the Randomized Controlled Trial (RCT).

STEPS IN DESIGNING AND CONDUCTING AN RCT Gathering the Research Team. ... Determining the Research Question. ... Defining Inclusion and Exclusion Criteria. ... Randomization. ... Determining and Delivering the Intervention. ... Selecting the Control. ... Determining and Measuring Outcomes. ... Blinding Participants and Investigators.

Randomized clinical trial (RCT) is regarded as the gold standard for assessing the relative effectiveness/efficacy of an experimental intervention, as it minimizes selection bias and threats to validity by estimating average causal effects.

The randomized controlled trial (RCT) is considered the "gold standard" experimental research design. Randomized controlled trials allow for researchers to establish causal associations between predictor, confounding, and outcome variables.

RCTs were only named as “gold standard” in 1982 by Alvan Feinstein and Ralph Horwitz in a paper published in The New England Journal of Medicine. At the end of the 19th and beginning of the 20th century, the rise of available hospitals allowed researchers to conduct trials.

The study protocol should contain in details the background, the objective, the rationale and the importance, as well as the design, the methodology, the Institutional Review Board approval, the informed consent and the statistical considerations of the RCT.