Get Thermodynamic Database For Protein Nucleic Acid Interactions ... - Bioinformatics Oxfordjournals

Nucleic acid sequences are stored in three primary sequence databases – GenBank, the EMBL nucleotide sequence database, and the DNA Data Bank of Japan – which exchange data every day. These databases also contain protein sequences that have been translated from DNA sequences.

The UniProt databases are the UniProt Knowledgebase (UniProtKB), the UniProt Reference Clusters (UniRef), and the UniProt Archive (UniParc). UniProt is a collaboration between the European Bioinformatics Institute (EMBL-EBI), the SIB Swiss Institute of Bioinformatics and the Protein Information Resource (PIR).

It contains the properties of the interacting protein and nucleic acid, bibliographic information and several thermodynamic parameters such as the binding constants, changes in free energy, enthalpy and heat capacity. ProNIT release 2.0 contains 4900 entries from 273 research articles, representing 158 proteins.

DDBJ. − The DNA Data Bank of Japan (DDBJ) was established in 1984. It is one of the three largest DNA databases in the world, forms an international DNA database with NCBI's GenBank and EMBL's EBI database. DDBJ's data information is updated every day. Nucleic Acid Databases - CD Genomics cd-genomics.com https://bioinfo.cd-genomics.com › nucleic-acid-databases cd-genomics.com https://bioinfo.cd-genomics.com › nucleic-acid-databases

The databases EMBL, NCBI and DDBJ are the three primary nucleotide sequence databases. They include sequences submitted directly by scientists and genome sequencing group, and sequences taken from literature and patents.

The Nucleic Acid Database is a relational database containing information about three-dimensional nucleic acid structures. The methods used for data processing, structure validation, database management and information retrieval, as well as the various services available via the World Wide Web, are described.

The Protein–Nucleic Acid Thermodynamics Database (PNATDB) is a database containing experimentally determined thermodynamic parameters along with sequence, structural, and function data, which is available free online. Thermodynamic database supports deciphering protein–nucleic acid ... sciencedirect.com https://.sciencedirect.com › article › abs › pii sciencedirect.com https://.sciencedirect.com › article › abs › pii

ProThermDB, thermodynamic Database for Proteins and Mutants (ProThermDB) contains more than 32,000 data of several thermodynamic parameters such as melting temperature, free energy obtained with thermal and denaturant denaturation, enthalpy change, and heat capacity change along with experimental methods and conditions ...

The Nucleotide database is a collection of sequences from several sources, including GenBank, RefSeq, TPA and PDB. Genome, gene and transcript sequence data provide the foundation for biomedical research and discovery.