Get Switching Ace-inhibitors

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin II receptor blockers (ARBs) are both first-choice groups of medications for treating high blood pressure. ACE inhibitors and ARBs have similar benefits, and both work equally well in the body. ARBs seem to cause less side effects than ACE inhibitors.

Therefore switching from ACE inhibitors to ARB might be beneficial in patients at risk or with COVID-19 in prevention of such sequelae when they are already on therapy affecting the Renin-Angiotensin System.

Side effects of ACE inhibitors may include: Dry cough. Increased potassium levels in the blood (hyperkalemia) Fatigue. Dizziness from blood pressure going too low. Headaches. Loss of taste.

However, we maintain that based on the data from ValHeFT and CHARM-Added, ARBs can be safely combined with ACE-inhibitors in patients with heart failure without serious risk of renal failure or hyperkalemia and regardless of background beta blocker therapy.

Yes. It's possible to switch from to . Your healthcare provider may recommend making the switch if you develop a bothersome cough with .

Therefore switching from ACE inhibitors to ARB might be beneficial in patients at risk or with COVID-19 in prevention of such sequelae when they are already on therapy affecting the Renin-Angiotensin System.

Blood pressure is reduced because ACE inhibitors block an enzyme early in the system, resulting in lower production of angiotensin, which can narrow blood vessels. ARBs, meanwhile, help blood vessels avoid constriction by blocking receptors to which angiotensin attaches.

ACE inhibitors and bradykinin Increased bradykinin levels are also responsible for ACE inhibitor treatment's most common side effect: a dry cough.