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  • Sn1 Vs Sn2 Vs E1 Vs E2 Chart

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Flowchart for E1, E2, Sn1, Sn2 Reactions NoCan the substrate form a good leaving group?no reactionYes Class of carbon 123 YesIs the nucleophile a strong base thats hindered?Strong base?Is the nucleophile.

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Comparing E1 and E2 mechanisms Reaction ParameterE2E1nucleophilehigh concentration of a strong baseweak basemechanism1-step2-steprate limiting stepanti-coplanar bimolecular transition statecarbocation formationrate lawrate = k[R-X][Base]rate = k[R-X]3 more rows • May 30, 2020

The identity of the nucleophile or base also determines which mechanism is favored. E2 reactions require strong bases. SN2 reactions require good nucleophiles. Therefore a good nucleophile that is a weak base will favor SN2 while a weak nucleophile that is a strong base will favor E2.

E2: favored by a strong base. SN2: favored by a good nucleophile (relatively weaker base) SN1/E1: It is hard to separate SN1 and E1 completely apart, because they both go through carbocation intermediates, and are favored by poor nucleophile/weak base, for example, H2O or ROH (solvolysis).

The identity of the nucleophile or base also determines which mechanism is favored. E2 reactions require strong bases. SN2 reactions require good nucleophiles. Therefore a good nucleophile that is a weak base will favor SN2 while a weak nucleophile that is a strong base will favor E2.

The most obvious way to distinguish E1 vs E2 is by looking at the number of steps in the mechanism. E1 takes place in two steps and has a carbocation intermediate; on the other hand, E2 takes place in one step and has no intermediate.

SN1 and E1 — the leaving group leaves first. SN2 and E2 — the leaving group leaves last. SN1 and SN2 — the X:⁻ attacks a carbon atom. E1 and E2 — the X:⁻ attacks a β hydrogen atom.

If the base/nucleophile is weak, then the mechanism is unimolecular – E1 or SN1. Let's summarize this again: if strong – SN2 or E2, if weak – SN1 or E1. Keeping this in mind, what we see is that essentially you will never have to choose between SN1 vs E2 and SN2 or E1 vs E2 and SN2.

Comparing the E1 vs SN1 Reactions E1 will generally be favored over SN1 when heat is applied. Secondly, in E1 reactions of alcohols where acid is added, the E1 is favored when the counter-ion of the acid is a poor nucleophile (e.g. H2SO4, H3PO4, TsOH)

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232