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  • Hla-b*57:01 Test Request Form - Homerton University Hospital

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HLAB*57:01 TEST REQUEST FORM PATIENT DETAILS Hospital/Clinic Number Sample ID Affix patient label here if available Patient ID Date of Birth Sex M F SAMPLE DETAILS Sample collection date D D M M M.

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This test checks whether you have a certain gene that may predispose you (or make you more likely) to having an allergic reaction from one of the HIV medications (called ). If you test positive for this gene, you should not be given .

The HLA-B*5701 screening test minimizes potential toxicities to by identifying patients who may be at risk of developing a hypersensitivity reaction.

The HLA-B*57:01 allele has been associated with hypersensitivity to , a highly effective nucleoside analog reverse-transcriptase inhibitor used to treat HIV infection and AIDS.

The FDA recommends screening for the HLA-B*57:01 allele before initiating therapy with . Genotyping is also critical when there is a clinical history of, or when the physician suspects, an hypersensitivity reaction.

The HLA-B*5701 allele occurs at approximately a 5 to 8% frequency in European populations, 1% frequency in Asian populations, and less than 1% frequency in African populations. In the United States, African Americans have a reported frequency of between 2 and 4%.

Interpretation. Positivity for human leukocyte antigen allele HLA-B*57:01 confers high risk for hypersensitivity to and higher risk of elevated alanine aminotransferase (ALT) levels in patient taking . For more information see Hypersensitivity Testing and Initial Patient Management Algorithm.

A test that detects the presence of HLA-B*5701. HLA-B*5701 is a genetic variation that is linked to hypersensitivity to the antiretroviral (ARV) drug . A person who tests positive for HLA-B*5701 should not use or any other -containing medicine.

Testing for HLA B 5701 most commonly uses a blood or saliva sample for sequence-based genotyping using a polymerase chain reaction. [3] Following these tests, the clinician will know if the patient is positive for the HLA B 5701 allele and be able to alter the treatment ingly.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232