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Leukocyte Depletion of Whole Blood Using CF11 Columns v1.2 Procedure Molecular Module WorldWide Antimalarial Resistance Network (WWARN) Suggested citation: Molecular Module. 2011. Leukocyte Depletion.

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Leukocyte depletion became one of the major tasks in blood transfusion within the last years. Both red cell and platelet preparations should be leukocyte depleted prior to transfusion to lower the risk of alloimmunization and CMV transmission [1,2].

Generally accepted indications for leukoreduction of blood products include: (1) reduction of HLA alloimmunization risk in patients who require long term platelet support, or for potential organ transplant recipients, (2) reduction of CMV transmission in at-risk patients, and (3) reduction of the rate of recurrent ...

Data sources: Published articles, books, and the author's experience. Data synthesis: Leukocyte removal filters are used to reduce complications associated with transfused white blood cells that are contained in units of red blood cells and platelets.

Leucocyte removal from blood components before transfusion by leucocyte depletion filters is known to prevent or at least delay leucocyte mediated adverse reactions. By use of third generation leucodepleted filters, the WBC count in the red cell and platelet concentrates has reduced to greater than 99.9%.

Blood donated to patients with blood diseases should always have the white cells removed by filtration, a process called leukoreduced or leukodepleted. Leukoreduction reduces the risks of: Fever and chills after transfusion. Not responding to platelet transfusions.

The flow cytometric analysis of leukocytes in whole blood usually requires isolation of leukocytes from other components of whole blood. Density gradient centrifugation and red blood cell lysis are the most commonly used methods to separate leukocytes but come with significant limitations.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
Industries
Forms in Spanish
Localized Forms
State-specific Forms
Forms Kit
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232