Get Certificate Of Analysis Bovine Serum Albumin Product No

Bovine serum albumin (also known as BSA or "Fraction V") is a serum albumin protein isolated from cows. ... In molecular biology, BSA is used to stabilize some restriction enzymes during digestion of DNA and to prevent adhesion of the enzyme to reaction tubes, pipet tips, and other vessels.

But fetal bovine serum (FBS), a blood byproduct of the meat industry, is a crucial building block for vaccines. So scientists making the vaccines need to know precisely which country the serum is coming from because the serum could contain specific bovine viruses or infectious agents.

BSA is one of the most well known proteins because of its widespread availability, similarity to HSA, use in medical formulations, and incorporation into many medical and biochemical assays. It is present in beef [14] and cow's milk [15].

Bovine serum albumin (BSA) is a major component of fetal bovine serum (FBS), which is commonly used as a culture medium during vaccine production. Because BSA can cause allergic reactions in humans the World Health Organization (WHO) has set a guidance of 50 ng or less residual BSA per vaccine dose.

When viruses are growing in cells, they need a source of nutritional ingredients. In some instances fetal bovine serum is the source of these growth factors. Once the viruses are harvested, they undergo multiple processing and purification steps before the final product is released to the market.

Bovine Serum Albumin (BSA) is used in a variety of laboratory applications including its function as a protein concentration standard, its function as a cell nutrient and its ability to stabilize enzymes during restriction digest.

Manufacturing Methods. Bovine serum albumin (BSA) is purified from serum using one of three different purification methods: cold-organic solvent fractionation, heat shock and ion exchange chromatography.

Manufacturing MethodsBovine serum albumin (BSA) is purified from serum using one of three different purification methods: cold-organic solvent fractionation, heat shock and ion exchange chromatography. ... Mannuzza and Montalto suggest that the best way to address this issue is to match the BSA to its intended use.