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(pI 5.7) is considerably higher than that of glutamic acid. Explain. Answer: (a) NH3 HO OH O O (b) NH2 O O O O (c) NH3 O OH O O (d) Because pI (pKa1+pKa2)/2, and obviously glutamine is much more basic than glutamic acid. It lead to the higher isoelectric point of glutamine . NH 24.2 The guanidino group H N C NH2 of arginine is one of the most strongly basic of all organic groups. Explain. Solution: The cation form of the guanidino group has three resonance structures as follows.

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