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IgG4-RD Disease Responder Index Date form completed e.g. 7 / July / 2050 / / Case number Scoring Rules This case report form refers to manifestations of disease activity present in the last 28 days Scoring 0 Normal or resolved Improved Persistent Unchanged from previous visit still active New / Recurrence Worsened despite treatment Definitions Organ/Site score The overall level of IgG4-RD activity within a specific organ system Symptomatic Is the.

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The IgG4-RD responder index (RI) is a disease activity tool modeled by Stone et al. [5, 6], wherein the sum of organ sites' score (each organ/site graded on a 0–4 scale) plus the serum IgG4 concentration score (0–4) yields the total RI score.

The rheumatologist should play a leading role in the diagnosis, management and treatment of all patients with IgG4-RD. Rheumatologists are expert in the assessment of multi-organ diseases and often have a broader approach to systemic illnesses than specialists who focus on single organs.

No single test can be used to diagnose IgG4-RD; instead, diagnosis depends on a combination of medical information, including history, physical findings, imaging, and laboratory results, supported by histopathology.

IgG4-RD is diagnosed on combination of typical radiological findings; elevation of serum IgG4 levels; histopathological findings of abundant infiltration of IgG4-positive plasma cells and lymphocytes, storiform fibrosis , and obliterative phlebitis ; association with other IgG4-related diseases; and response to ...

IgG4 serves as an indicator of the extent of allergen exposure and is produced after long-term exposure to an antigen.

IgG4-related disease is an immune-mediated condition, meaning that it involves the occurrence of disease in organs as the result of a dysregulated immune system. Increasing evidence suggests that IgG4-RD is an autoimmune condition, much like rheumatoid arthritis and systemic lupus erythematosus.

The reference interval of serum IgG4 in adults has been recommended as 0.052–1.250 g/L with the upper limit being 0.86–1.35 g/L, and IgG4 levels over 2 g/L have been reported in a few healthy subjects (17-19).

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232