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  • Issls Prize Winner: Microstructure And Mechanical Disruption Of The - Med Nyu

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SPINE Volume 33, Number 25, pp 2711?2720 ?2008, Lippincott Williams & Wilkins ISSLS Prize Winner: Microstructure and Mechanical Disruption of the Lumbar Disc Annulus Part II: How the Annulus Fails.

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The annulus fibrosus is the tough circular exterior of the intervertebral disc that surrounds the soft inner core, the nucleus pulposus. This outer portion is composed of a ring of ligament fibers that encases the inner core of the disc and securely connects the spinal vertebrae above and below the disc.

Nucleus pulposus mechanics The nucleus pulposus is a highly hydrated gel with important material properties that include swelling pressure, compression modulus, permeability, and shear modulus. The nucleus has a large water and proteoglycan content.

The inter- vertebral disc serves primarily to allow movement between adjacent vertebral bodies, to absorb shock, and to transmit loads through the vertebral column. The complex morphology and structure of the intervertebral disc of the lumbar spine reflects these functions.

The nucleus pulposus is a highly hydrated gel with important material properties that include swelling pressure, compression modulus, permeability, and shear modulus. The nucleus has a large water and proteoglycan content.

Two characteristic features of the nucleus pulposus microenvironment are 1) lack of vascularization, which creates a physiologically hypoxic environment, and 2) high content of water-binding proteoglycans, which elevates osmotic pressure outside of cells.

Lumbar intervertebral discs (IVDs) are complex structures that consist of three main components; the soft, deformable nucleus pulposus (NP), surrounded by the fibrous concentric layers of the annulus fibrosus (AF), and finally, the thin cartilaginous end plates that enclose the NP and AF cranially and caudally.

The inter- vertebral disc serves primarily to allow movement between adjacent vertebral bodies, to absorb shock, and to transmit loads through the vertebral column.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232