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Association of sperm apoptosis and DNA ploidy with sperm chromatin quality in human spermatozoa Reda Z. Mahfouz, M.D.,a Rakesh K. Sharma, Ph.D.,a Tamer M. Said, M.D.,b Juris Erenpreiss, M.D.,c and.

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The sperm head contains the genetic material. The head of the sperm contains the nucleus.

Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure.

Apoptosis as a marker of semen quality Apoptosis of sperm was considered a potentially useful indicator of male fertility (21). Loss of germ cell, which happens via apoptosis, is a prevailing mechanism during spermatogenesis and is regulated by the expression levels of p53, p21, Bcl-2, FAS, and caspases (82).

The sperm DNA (deoxyribonucleic acid) is packed with specific small, basic proteins into a tight, almost crystalline status that is at least six times more condensed than in mitotic chromosomes [4]. Spermatids develop into spermatozoa through process of spermatogenesis.

The sperm chromatin structure assay (SCSA) is a new diagnostic tool that can detect sperm samples that have a high degree of DNA fragmentation (small breaks in the sperm chromosomes). Samples with a high percentage of DNA fragmented sperm (>30%) has been associated with a nearly four-fold reduction in term pregnancies.

Major sperm protein (MSP) is a nematode specific small protein of 126 amino acids with a molecular weight of 14 kDa.

Sperm chromatin/DNA integrity is essential for the accurate transmission of paternal genetic information, and normal sperm chromatin structure is important for sperm fertilizing ability.

These proteins are called histones, and the resulting DNA-protein complex is called chromatin.

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Form Packages
Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
Industries
Forms in Spanish
Localized Forms
State-specific Forms
Forms Kit
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232