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In total, there are 20 core STRs recognized for forensic DNA testing, including the original 13. These full set of STRs are vital for achieving accurate and reliable DNA profiles. The Validation of Multiplex Polymorphic STRs optimizes the analysis of these markers, enhancing the quality of results. This comprehensive approach supports various applications in forensic science and legal evidence collection.

The Combined DNA Index System (CODIS) uses 20 core STRs for identification purposes. CODIS facilitates the comparison of DNA profiles across different jurisdictions, aiding law enforcement in solving crimes. The Validation of Multiplex Polymorphic STRs ensures that these 20 STRs are accurately analyzed and reported. This integration makes CODIS an effective tool for improving public safety and criminal justice outcomes.

Typically, 13 core STRs are examined in forensic DNA analysis. This examination allows for a comprehensive understanding of an individual's genetic profile. The Validation of Multiplex Polymorphic STRs enhances the reliability of DNA results, ensuring that the analysis meets the rigorous standards required in legal cases. With each core STR offering unique information, together they provide a robust identification method.

The 13 core Short Tandem Repeats, or STRs, are specific genetic markers used in DNA profiling. These markers include D3S1358, D5S818, D7S820, and several others. Validation of Multiplex Polymorphic STRs is essential for accurate forensic analysis, making these 13 STRs critical for identification. Understanding these markers helps in numerous applications, including criminal investigations and paternity testing.

1.13 Multiplex PCR Since first described by Chamberlain et al. (1988), it has had many applications and is typically used for genotyping, where simultaneous analysis of multiple markers is required, for detection of pathogens or genetically modified organisms, or for microsatellite analyses.

PCR (Polymerase Chain Reaction) is a revolutionary method developed by Kary Mullis in the 1980s. PCR is based on using the ability of DNA polymerase to synthesize new strand of DNA complementary to the offered template strand.

This new technique is a refinement of the original Polymerase Chain Reaction (PCR) developed by Kary Mullis and coworkers in the mid 80:ies [Saiki, R.K., et al., 1985.

Multiplex PCR is a widespread molecular biology technique for amplification of multiple targets in a single PCR experiment. In a multiplexing assay, more than one target sequence can be amplified by using multiple primer pairs in a reaction mixture.

Multiplex PCR It was first described in 1988 as a method to detect deletions in the dystrophin gene and has also been used with the steroid sulfatase gene. In 2008 multiplex-PCR was used for analysis of microsatellites and SNPs (Single Nucleotide Polymorphism).