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Annu. Rev. Genomics Hum. Genet. 2003. 4:119 41 doi: 10.1146/annurev.genom.4.070802.110352 First published online as a Review in Advance on June 4, 2003 FORENSICS AND MITOCHONDRIAL DNA: Applications,.

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Mitochondrial DNA (mtDNA) analysis is used by forensic scientists when samples such as teeth, bones, and hairs without a follicle (root) are collected from crime scenes or disaster areas. MtDNA is also used when nuclear DNA is present in very low quantities or is highly degraded and does not provide a full STR profile.

How is mitochondrial DNA (mtDNA) typing used in forensic science? An unknown mtDNA sample is matched to a sample of nuclear DNA that was found at a crime scene.

Mitochondrial DNA is maternally inherited. Additionally the maternal inheritance of mtDNA allows scientists to compare the mtDNA profile of a set of remains to that of reference samples from individuals such as the mother, brother(s), sister(s), or any other maternally related individuals of a missing person.

mtDNA was used as evidence for the first time in US courts in 1998, and it has since become a staple in many cases where DNA evidence is presented.

Mitochondrial DNA is the circular chromosome found inside the cellular organelles called mitochondria. Located in the cytoplasm, mitochondria are the site of the cell's energy production and other metabolic functions. Offspring inherit mitochondria — and as a result mitochondrial DNA — from their mother.

mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low.

The major disadvantage using mtDnA is the lower discrimination power compared to multiple nuclear DnA markers. In contrast to the nuclear genome, due to the uniparental (maternal) mode of inheritance, no individual has unique mtDnA.

In anthropological genetics, mtDNA is useful to trace geographic distribution of genetic variation, for the investigation of expansions, migrations and other pattern of gene flow. mtDNA is widely applicated in forensic science. It is a powerful implement to identify human remains.

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Adoption
Bankruptcy
Contractors
Divorce
Home Sales
Employment
Identity Theft
Incorporation
Landlord Tenant
Living Trust
Name Change
Personal Planning
Small Business
Wills & Estates
Packages A-Z
Form Categories
Affidavits
Bankruptcy
Bill of Sale
Corporate - LLC
Divorce
Employment
Identity Theft
Internet Technology
Landlord Tenant
Living Wills
Name Change
Power of Attorney
Real Estate
Small Estates
Wills
All Forms
Forms A-Z
Form Library
Customer Service
Terms of Service
DMCA Policy
About Us
Blog
Affiliates
Contact Us
Privacy Notice
Delete My Account
Site Map
All Forms
Search all Forms
Industries
Forms in Spanish
Localized Forms
Legal Guides
Real Estate Handbook
All Guides
Prepared for You
Notarize
Incorporation services
Our Customers
For Consumers
For Small Business
For Attorneys
Our Sites
US Legal Forms
USLegal
FormsPass
pdfFiller
signNow
airSlate workflows
DocHub
Instapage
Social Media
Call us now toll free:
1-877-389-0141
As seen in:
  • USA Today logo picture
  • CBC News logo picture
  • LA Times logo picture
  • The Washington Post logo picture
  • AP logo picture
  • Forbes logo picture
© Copyright 1997-2025
airSlate Legal Forms, Inc.
3720 Flowood Dr, Flowood, Mississippi 39232