Control Age Transcript For Free

The coordinated regulation of p53, target of rapamycin (TOR), and insulin/insulin-like growth factor 1 (IGF-1) pathways. The p53, TOR, and insulin/IGF-1 pathways are three important pathways that regulate aging and longevity. The decreased TOR and insulin/IGF-1 signaling promotes longevity.

Aging is not and cannot be programmed. Instead, aging is a continuation of developmental growth, driven by genetic pathways such as mTOR. Ironically, this is often misunderstood as a sort of programmed aging.

Genes that promote ageing include some that encode yolk proteins, consistent with a link between ageing and reproduction. Another pro-ageing protein is the insulin-like INS-7, which, by binding to the insulin/IGF-1 receptor (DAF-2), may repress DAF-16 on the same and other cells.

Our DNA changes as we age. Some of these changes are epigeneticthey modify DNA without altering the genetic sequence itself. Epigenetic changes affect how genes are turned on and off, or expressed, and thus help regulate how cells in different parts of the body use the same genetic code.

What is transcription? Transcription is the process by which the information in a strand of DNA is copied into a new molecule of messenger RNA (mRNA). DNA safely and stably stores genetic material in the nuclei of cells as a reference, or template.

Transcription is the first step in gene expression. It involves copying a gene's DNA sequence to make an RNA molecule. Transcription is performed by enzymes called RNA polymerases, which link nucleotides to form an RNA strand (using a DNA strand as a template).

If a gene is not transcribed in a cell, it can't be used to make a protein in that cell. If a gene does get transcribed, it is likely going to be used to make a protein (expressed). In general, the more a gene is transcribed, the more protein that will be made.