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What is a transcript and how is it related to a gene? Transcripts are defined as RNA molecules that are made from a DNA template.While most genes are associated with multiple transcripts, each transcript is only assigned to a single gene (at least in databases).

The canonical transcript is defined as either the longest CDS, if the gene has translated transcripts, or the longest cDNA. If you were to implement this and compare it with the knownCanonical table, you would see a lot of exceptions to the rule.

Isoforms refers to different versions of protein from the same gene in this setting, and transcript variants refers to different versions of mRNA transcript from the same gene.

RefSeq Select in Prokaryotes For prokaryotes, RefSeq Select is defined as proteins annotated on RefSeq reference and representative genomes. In most cases there is only one reference or representative genome per prokaryote species.It currently includes about one-third of the prokaryote RefSeq protein dataset.

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A red transcript comes from either the Ensembl automatic annotation pipeline or manual curation by the VEGA/Havana project. A gold, or merged, transcript is identical between Ensembl automated annotation and VEGA/Havana manual curation. Only human, mouse, and zebrafish will have gold transcripts.

Transcription is the process of making an RNA copy of a gene sequence. This copy, called a messenger RNA (mRNA) molecule, leaves the cell nucleus and enters the cytoplasm, where it directs the synthesis of the protein, which it encodes.