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S Diseases 1990, 3:409-413 D T IC ELECTE AD-A227 374 k1 Malaria is a major world health problem with hundreds of millions of cases and millions of deaths per year. Research on malaria concentrates on Plasmodiumftalciparum: this parasite is the major cause of the fatal disease. This review highlights research in the areas of vaccine development. pathophysiology of disease, drug resistance. and drug therapy. (/"') the parasite during its development in the mosquito. They infected mosquitoes wit.

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