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Typke, and Wolfgang Baumeister Department of Molecular Structural Biology, Max-Planck-Institute for Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany Electron tomography is the only technique available that allows us to visualize the three-dimensional structure of unfixed and unstained cells currently with a resolution of 6 8 nm, but with the prospect to reach 2 4 nm. This raises the possibility of detecting and identifying specific macromolecular complexes within their cel.
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