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Opher G. Winter,3 Alison Maresh, Xuesong Zhao, and Liqun Luo1 Department of Biological Sciences Stanford University Stanford, California 94305 Summary Mechanisms that regulate axon branch stability are largely unknown. Genome-wide analyses of Rho GTPase activating protein (RhoGAP) function in Drosophila using RNA interference identified p190 RhoGAP as essential for axon stability in mushroom body neurons, the olfactory learning and memory center. p190 inactivation leads to axon branch retractio.

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