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- Vital And Health Statistics; Series 11, No. 204 (July 1977). Tuberculin Skin Test Reaction Among
Get Vital And Health Statistics; Series 11, No. 204 (July 1977). Tuberculin Skin Test Reaction Among
From the National Health Survey; no. 204) (DHEW publication; no. (HRA) 77-1649) Includes bibliographical references. 1. Tuberculin test-United States-Statistics. 2. Health surveys-United States. I. Roberts, Jean, joint author. II. Title. III. S eries: United States. National Center for Health Statistics. Vital and health statistics: Series. 11, Data from the National Health Survey, Data from the health examination survey; no. 204. IV. Series: United States. Dept. of Health, Education, and Wel.
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Noninstitutionalized FAQ
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Drug Summary Tubersol (tuberculin purified protein derivative) is a cell-free purified protein derived from Mycobacterium tuberculosis indicated as an aid in the detection of infection with M. tuberculosis. Tubersol may be available in generic form.
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In general, the sensitivity of the TST for detection of active TB ranges from 65% to 94%, but in critically ill patients with disseminated disease, the sensitivity decreases to only 50%. Thus, a negative TST reaction can never exclude a diagnosis of TB.
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The specificity of the skin test is approximately 99.98% and therefore animals identified as positive are highly likely to be truly infected with M. bovis, regardless of their post mortem or culture result.
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Indication: To aid in the diagnosis of tuberculosis infection in persons at increased risk of developing active disease.
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Tubersol produced slightly smaller reactions, and Aplisol slightly larger reactions, than did PPD-S1, but these differences in reaction sizes did not result in significant differences in skin test interpretation; the specificities of both commercial reagents were high (>98%) and similar to that of PPD-S1.
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Aplisol (tuberculin PPD, diluted) is a sterile aqueous solution of a purified protein fraction for intradermal administration as an aid in the diagnosis of tuberculosis. The solution is stabilized with polysorbate (Tween) 80, buffered with potassium and sodium phosphates and contains 0.25% phenol as a preservative.
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Tubersol is a clear, colourless solution for injection. Tuberculin PPD is indicated as an aid in the detection of infection with Mycobacterium tuberculosis. The Mantoux test is performed by injection intradermally, with a syringe and needle, 0.1 mL of Tuberculin PPD.
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