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Y Zhijian Chen, Jeremiah Hagler, 2 Vito J. Palombella, 1 Franeesco Melandri, 1 David Seherer, 3 Dean Ballard, 3 and T o m Maniatis 2 Myogenics, Inc., Cambridge, Massachusetts 02139 USA; 2Harvard University, Department of Molecular and Cellular Biology, Cambridge, Massachusetts 02138 USA 3Howard Hughes Medical Institute, Department of Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 USA The transcription factor NF-KB is sequestered in the cyto.

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