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"Department of Pathology, University of Geneva, Geneva 4, Switzerland ABSTRACT The secretion of plasminogen activators has been implicated in the controlled extracellular proteolysis that accompanies cell migration and tissue remodeling. We found that the human plasminogen activator (Uk) (Mr 55,000 form) binds rapidly, specifically, and with high affinity to fresh human blood monocytes and to cells of the monocyte line U937. Upon binding, Mr 55,000 Uk was observed to confer high plas.
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Keywords relevant to A Cellular Binding Site For The Mr 55000 Form Of The Human ...
- Monocytes
- BSA
- PBS
- Macrophages
- RPMI
- unlabeled
- monocyte
- plasmin
- thrombin
- 25i
- mononuclear
- extracellular
- EGF
- vassalli
- murine
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