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E,1 Jean-Michel Deniau,2 Jacques Glowinski,1 and Anne-Marie Thierry1 Chaire de Neuropharmacologie, Institut National de la Sante et de la Recherche Me dicale U114, Colle ge de France, 75231 Paris Cedex 05, France, and 2Universite Pierre et Marie Curie, De partement de Neurochimie-Neuroanatomie, Institut des Neurosciences, Unite de Recherche Mixte 7624, 75230 Paris Cedex 05, France 1 The prelimbic/medial orbital areas (PL/MO) of the rat prefrontal cortex are connected to substantia nigr.
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Glutamatergic FAQ
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The basal ganglia are a group of subcortical nuclei which integrate information from widespread cortical areas and in turn project their outputs back to the cerebral cortex (Alexander et al., 1990).
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The active maintenance of the memory is in prefrontal cortex (PFC), and the updating signals (and updating policy more generally) come from the striatum units (a subset of basal ganglia units). PVLV provides reinforcement learning signals to train up the dynamic gating system in the basal ganglia.
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The prefrontal cortex (PFC) has extensive connections with other cortical and subcortical regions that are organized in a topographical manner, such that regions that regulate emotion are situated ventrally and medially (green area in part a of the figure) and regions that regulate thought and action are situated more ...
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The active maintenance of the memory is in prefrontal cortex (PFC), and the updating signals (and updating policy more generally) come from the striatum units (a subset of basal ganglia units). PVLV provides reinforcement learning signals to train up the dynamic gating system in the basal ganglia.
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In summary, when a given motor pattern is computed by the cerebral cortex, it is first conveyed to the basal ganglia via glutamatergic projections to the striatum, with the purpose of releasing the intended movement and suppressing the unintended ones.
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In short, one can think of the overall influence of the basal ganglia on the frontal cortex as “releasing the brakes” for motor actions and other functions. The basal ganglia are important for initiating motor movements, but not for determining the detailed properties of those movements.
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The basal ganglia are a group of subcortical nuclei which integrate information from widespread cortical areas and in turn project their outputs back to the cerebral cortex (Alexander et al., 1990).
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In general then, there exist a number of cortical loops through the basal ganglia that involve prefrontal association cortex and limbic cortex. Through these loops, the basal ganglia are thought to play a role in cognitive function that is similar to their role in motor control.
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Keywords relevant to Relationships Between The Prefrontal Cortex And The Basal Ganglia In The Rat Physiology Of The
- subthalamic
- nqx
- nigral
- cortico
- bicuculline
- Maurice
- glutamatergic
- neurosci
- Deniau
- inhibitory
- 1999
- striato
- pallidum
- 1994
- GABAergic
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