- US Legal Forms
- Form Library
- More Forms
- More Multi-State Forms
- Neuropsychopharmacology (2007) 32, 21432151 & 2007 Nature Publishing Group All Rights Reserved
Get Neuropsychopharmacology (2007) 32, 21432151 & 2007 Nature Publishing Group All Rights Reserved
D to the 5-HTT Gene Polymorphism in Treatment-Resistant Depression Ikuko Kishida1,2, Eleni Aklillu*,1, Chiaki Kawanishi2, Leif Bertilsson1 and Hans A gren3 1 Division of Clinical Pharmacology, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden; 2Department of Psychiatry, Yokohama City University School of Medicine, Yokohama, Japan; 3Section of Psychiatry, Department of Clinical Neuroscience, Karolinska University Hospital Huddin.
How It Works
-
Open form follow the instructions
-
Easily sign the form with your finger
-
Send filled & signed form or save
Experience a faster way to fill out and sign forms on the web. Access the most extensive library of templates available.
Neuropsychopharmacology FAQ
-
Researchers don't know the exact cause of TRD. As depression has many contributing factors — like genetics and brain chemistry — so does treatment-resistant depression. They think that chronic stress may contribute to TRD by changing the function of your hypothalamic-pituitary-adrenal (HPA) axis.
-
Severe childhood physical or sexual abuse, childhood emotional and physical neglect, and severe life stress are probably all risk factors. Losing a parent early in life probably also increases risk to some extent. If someone has a family history of depression, are they at very high risk?
-
Researchers don't know the exact cause of TRD. As depression has many contributing factors — like genetics and brain chemistry — so does treatment-resistant depression. They think that chronic stress may contribute to TRD by changing the function of your hypothalamic-pituitary-adrenal (HPA) axis.
-
However, younger age, fatigue, substance use disorders, anxiety, other psychiatric conditions, insomnia, severity of depression, melancholic clinical features, inflammatory system activation, abnormal neural activity, neurotransmitter dysfunction, unemployment, and pain have been shown to be risk factors for TRD ( ...
-
Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events. It's believed that several of these forces interact to bring on depression.
-
There are a number of reasons why people may not get well when treated for psychiatric symptoms. Some of the more common causes in traditional psychiatry are misdiagnosis, being unaware of co-occurring conditions, ignoring condition subtypes, intolerance to medication, and lack of compliance.
MHPG Related content
-
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
Neurobehavioral Effects of -α in Patients with...
by MD McNutt · 2012 · Cited by 77 — In Morasco's 2007 study (Morasco et al, 2007)...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
It is illegal to post this copyrighted PDF on any...
Neuropsychopharmacology. 2007;32(10):2143–2151.PubMed doi:10.1038/sj.npp.1301336. 32...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
Intranasal Immune Challenge Induces Sex-Dependent...
by LH Tonelli · 2008 · Cited by 152 — These results suggest that peripheral...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
Neurobehavioral Effects of -α in Patients with...
by MD McNutt · 2012 · Cited by 77 — In Morasco's 2007 study (Morasco et al, 2007)...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
It is illegal to post this copyrighted PDF on any...
Neuropsychopharmacology. 2007;32(10):2143–2151.PubMed doi:10.1038/sj.npp.1301336. 32...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151 & 2007 Nature Publishing Group All rights...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
It is illegal to post this copyrighted PDF on any...
Neuropsychopharmacology. 2007;32(10):2143–2151.PubMed doi:10.1038/sj.npp.1301336. 32...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
It is illegal to post this copyrighted PDF on any...
Neuropsychopharmacology. 2007;32(10):2143–2151.PubMed doi:10.1038/sj.npp.1301336. 32...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
Neurobehavioral Effects of -α in Patients with...
by MD McNutt · 2012 · Cited by 77 — In Morasco's 2007 study (Morasco et al, 2007)...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Neurobehavioral Effects of -α in Patients with...
by MD McNutt · 2012 · Cited by 77 — In Morasco's 2007 study (Morasco et al, 2007)...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
It is illegal to post this copyrighted PDF on any...
Neuropsychopharmacology. 2007;32(10):2143–2151.PubMed doi:10.1038/sj.npp.1301336. 32...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
by I Kishida · 2007 · Cited by 32 — Neuropsychopharmacology volume 32, pages...
Learn more -
Monoamine metabolites level in CSF is related to...
We investigated the influence of 5-HTT-linked polymorphic region (5-HTTLPR) and 5-HTT 17...
Learn more -
Monoamine Metabolites Level in CSF is Related to...
Neuropsychopharmacology (2007) 32, 2143–2151. & 2007 Nature Publishing Group All rights...
Learn more -
A Review of the Conceptualisation and Risk Factors...
by JA Murphy · 2017 · Cited by 66 — Depressed patients classified with the melancholic...
Learn more -
The influence of serotonin transporter...
by TW Lee · 2011 · Cited by 29 — The serotonin transporter gene (5-HTT) is a key...
Learn more -
Cerebrospinal fluid monoamine metabolite...
by S Ogawa · 2018 · Cited by 42 — We performed a meta-analysis of historic evidence to...
Learn more -
Neurobehavioral Effects of -α in Patients with...
by MD McNutt · 2012 · Cited by 77 — In Morasco's 2007 study (Morasco et al, 2007)...
Learn more -
Elevated Brain Serotonin Turnover in Patients With...
by DA Barton · 2008 · Cited by 263 — Neuropsychopharmacology 2007;32 (10) 2143...
Learn more -
...
European Neuropsychopharmacology, 10.1016/s0924-977x(03)92271-1, 2003, 13, S417 ... 2007...
Learn more -
A review of the conceptualisation and risk factors...
by JA Murphy · 2017 · Cited by 66 — (2007). Interaction between 5-HT1A and BDNF...
Learn more
Related links form
Use professional pre-built templates to fill in and sign documents online faster. Get access to thousands of forms.
Keywords relevant to Neuropsychopharmacology (2007) 32, 21432151 & 2007 Nature Publishing Group All Rights Reserved
- polymorphisms
- Polymorphism
- genotype
- 5-HTTVNTR
- 1996
- 1998
- neuropsychopharmacology
- MHPG
- MDD
- Kishida
- ANCOVA
- genotypic
- nmol
- serotonergic
- Heinz
USLegal fulfills industry-leading security and compliance standards.
-
VeriSign secured
#1 Internet-trusted security seal. Ensures that a website is free of malware attacks.
-
Accredited Business
Guarantees that a business meets BBB accreditation standards in the US and Canada.
-
TopTen Reviews
Highest customer reviews on one of the most highly-trusted product review platforms.