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It claims more lives than lung cancer, and is the second biggest killer after cardiovascular disease. There are an estimated 123,000 cases of sepsis per year in England, and around 36,800 associated deaths.

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Please cite these tools as: Nutbeam T, Daniels R on behalf of the UK Sepsis Trust, Available at sepsistrust.org/professional-resources/clinical/, date last accessed 23rd March 2023.

Sepsis affects approximately 1.7 million adults in the United States each year and potentially contributes to more than 250 000 deaths. Various studies estimate that sepsis is present in 30% to 50% of hospitalizations that culminate in death.

Sepsis always starts with an infection. In the UK this is usually a bacterial infection but it can also sometimes be a viral infection such as 'Flu'. The commonest types of infection that can lead to sepsis include: Pneumonia (infection in the lungs often also called chest infection)

Every 3 seconds, someone in the world dies of sepsis. In the UK alone, 245,000 people are affected by sepsis with at least 48,000 people losing their lives in sepsis-related illnesses every year. This is more than breast, bowel and prostate cancer combined. Globally, sepsis claims 11 million lives a year.

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Up to 48,000 deaths in the UK every year The IHME study again corroborated this figure, suggesting that the UK loses 48,000 people to sepsis each year. Again, during a pandemic we would expect this figure to be higher.