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The Basics. A half-life is the time taken for something to halve its quantity. The term is most often used in the context of radioactive decay, which occurs when unstable atomic particles lose energy. Twenty-nine elements are known to be capable of undergoing this process.

The quantity of radioactive nuclei at any given time will decrease to half as much in one half-life. For example, if there were 100g of Cf-251 in a sample at some time, after 800 years, there would be 50g of Cf-251 remaining. After another 800 years (1600 years total), there would only be 25g remaining.

The half-life is then determined from the fundamental definition of activity as the product of the radionuclide decay constant, λ, and the number of radioactive atoms present, N. One solves for λ and gets the half-life from the relationship λ = ln2/T1/2.

The rules of evidence related to speed exist because of what is considered the “half-life” of evidence. All evidence changes character over time. The properties, characteristic, condition, etc. that a piece of evidence has today will evolve and become different tomorrow.

Understanding the concept of half-life is useful for determining excretion rates as well as steady-state concentrations for any specific drug. Different drugs have different half-lives; however, they all follow this rule: after one half-life has passed, 50% of the initial drug amount is removed from the body.